There are currently three projects in my laboratory.
One focuses on understanding how plants are able to change their growth
habits in response to environmental cues, such as light and nutrient availability.
Another is in the area of phytoremediation, which is the use of plants
to remove pollutants from the environment. Recently, we are also exploring
the role molecular motors play in regulating organ production during development.
Growth
in plants can be described as a combination of cell proliferation and
cell expansion. And, cell proliferation in plants mostly takes place in
regions called meristems. Cell divisions in meristems are highly regulated.
While it is clear that the cell cycle is tightly controlled by the activity
of the a protein complex containing a cyclin and a cyclin-dependent kinase,
the molecular details of this regulatory process remains unclear in plants.
Moreover, how a signal from the environment, such as the position or existence
of light, is processed to affect cell division rates is unknown. My laboratory
uses cellular, molecular, and genetic tools on the model plant Arabidopsis
thaliana to answer questions related to cell division control. For example,
how is cell division regulated during photomorphogenesis? We are analyzing
cell division pattern in mutants defective in light and dark developmental
programs to make conclusions about the role these molecules play in controlling
cell division The second area of research is in phytoremediation. The focus here is
to identify genes that can be used in the genetic engineering of plants
to clean up soils that are contaminated with polycyclic aromatic hydrocarbons
(PAHs), which are major pollutant byproducts of oil base manufacturing.
Using Arabidopsis thaliana as a model system, we are isolating mutants
that are able to degrade or are hypersensitive to the pollutants with
the hope of manipulating processes that allow for plant mediate degradation
of pollutants.
The third area of research is a collaboration with Joe Gindhart at the
University of Richmond and my lab. We have identified Arabidopsis mutants
that are defective in processes associated with the proteins kinesins,
microtubule motor proteins. We are currently analyzing phenotypes of null
mutations in several members of this very large multigene family.
My
teaching interests are in plant molecular biology and physiology. I participate
in undergraduate and graduate courses related to plant molecular biology,
plant physiology, developmental biology, biotechnology and plant hormone
biology. I am an advocate of inquiry based learning that incorporates
hand-on laboratory experiences. I am also active in training and mentoring
student groups that are underrepresented in the sciences.